Motif ID: NFY{A,B,C}.p2

Z-value: 2.467


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFYBhg19_v1_chr12_-_104531875_1045320390.422.6e-01Click!
NFYChg19_v1_chr1_+_41157493_411575240.304.3e-01Click!
NFYAhg19_v1_chr6_+_41040687_41040712-0.235.6e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_26045611 3.560 NM_003531
HIST1H3C
histone cluster 1, H3c
chr19_+_38893766 2.188 NM_174905
FAM98C
family with sequence similarity 98, member C
chr1_+_151763174 1.767


chr6_+_26199712 1.728 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr6_-_26043884 1.576 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr2_-_240322692 1.180 HDAC4
histone deacetylase 4
chr2_-_240322620 1.168 NM_006037
HDAC4
histone deacetylase 4
chr4_+_88720701 1.109 NM_004967
IBSP
integrin-binding sialoprotein
chr16_+_72698996 1.076


chr6_+_31783314 1.025 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr1_-_6052481 1.018 NM_015102
NPHP4
nephronophthisis 4
chr11_-_45939361 1.018 PEX16
peroxisomal biogenesis factor 16
chrX_+_49126299 1.010 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory subunit 3F

chr17_-_8059637 1.009 PER1
period homolog 1 (Drosophila)
chr10_-_15130773 1.007 NM_001039844
ACBD7
acyl-CoA binding domain containing 7
chr19_-_49140569 0.998 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr4_-_120375770 0.979


chr6_+_31783280 0.966 NM_005345
HSPA1A
heat shock 70kDa protein 1A
chr9_-_34329151 0.963 NM_194313
KIF24
kinesin family member 24
chr11_-_67275549 0.953 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr5_+_108084638 0.930 FER
fer (fps/fes related) tyrosine kinase
chr6_+_31783530 0.928 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chrX_+_49126326 0.910 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr21_-_34852282 0.902 NM_006134
TMEM50B
transmembrane protein 50B
chr19_+_38893804 0.902 FAM98C
family with sequence similarity 98, member C
chr17_+_74261280 0.901 NM_182565
FAM100B
family with sequence similarity 100, member B
chr19_+_19174792 0.893 NM_178526
SLC25A42
solute carrier family 25, member 42
chr17_-_80656461 0.884 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr21_-_34852226 0.877 TMEM50B
transmembrane protein 50B
chrX_+_49047887 0.872


chr6_+_31795395 0.871 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr16_-_1832576 0.854 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr16_+_4743693 0.829 NM_001193452
NM_032349
NUDT16L1

nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1

chr17_-_7197896 0.820 YBX2
Y box binding protein 2
chrX_+_49126480 0.816 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr19_-_2944894 0.803 NM_021217
ZNF77
zinc finger protein 77
chr17_+_77071002 0.801 NM_001042573
ENGASE
endo-beta-N-acetylglucosaminidase
chr3_-_27410852 0.799 NM_199347
NEK10
NIMA (never in mitosis gene a)- related kinase 10
chr16_-_1832571 0.785 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr19_-_14606939 0.776 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr16_-_74455239 0.754 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chrX_+_52926334 0.741 FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chr16_+_4743709 0.733 NUDT16L1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr19_+_36266366 0.730 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr14_-_75389901 0.728 RPS6KL1
ribosomal protein S6 kinase-like 1
chr19_-_14606893 0.721 GIPC1
GIPC PDZ domain containing family, member 1
chr1_-_6052410 0.721 NPHP4
nephronophthisis 4
chr16_-_1832304 0.706 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_227127937 0.698 NM_020247
ADCK3
aarF domain containing kinase 3
chr19_+_14640413 0.697 TECR
trans-2,3-enoyl-CoA reductase
chr1_-_149814264 0.695 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr21_-_47743753 0.686 NM_058180
C21orf58
chromosome 21 open reading frame 58
chr21_-_34852163 0.675 TMEM50B
transmembrane protein 50B
chr1_-_16161279 0.671


chr17_+_46048406 0.670 NM_176096
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr14_+_53019865 0.665 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr2_-_239148626 0.664 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr6_-_27858569 0.658 NM_003535
HIST1H3J
histone cluster 1, H3j
chr1_+_227127999 0.651 ADCK3
aarF domain containing kinase 3
chr17_+_1619816 0.650 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr19_+_13001966 0.650 NM_000159
NM_013976
GCDH

glutaryl-CoA dehydrogenase

chr4_-_7044664 0.650 NM_153376
CCDC96
coiled-coil domain containing 96
chr12_-_56727720 0.639 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr4_+_156680125 0.635 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr11_+_64879294 0.633 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr16_+_1833003 0.633


chr1_+_227127959 0.629 ADCK3
aarF domain containing kinase 3
chr12_+_49716970 0.628 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr19_+_14640363 0.611 NM_138501
TECR
trans-2,3-enoyl-CoA reductase
chr6_-_26033795 0.611 NM_003513
HIST1H2AB
histone cluster 1, H2ab
chr7_-_65235688 0.605 LOC441242
uncharacterized LOC441242
chr11_+_66406189 0.601 RBM4
RNA binding motif protein 4
chr12_-_6665220 0.596 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr19_+_14640406 0.595 TECR
trans-2,3-enoyl-CoA reductase
chr3_-_59035700 0.594 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr16_-_1876528 0.593 HAGH
hydroxyacylglutathione hydrolase
chr19_-_55677919 0.593 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr8_+_118532953 0.587 NM_080651
MED30
mediator complex subunit 30
chr17_+_74261431 0.584 FAM100B
family with sequence similarity 100, member B
chr6_-_32095974 0.579 ATF6B
activating transcription factor 6 beta
chr1_-_150602020 0.579 ENSA
endosulfine alpha
chr6_+_26104103 0.578 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr5_-_107717798 0.577 NM_001163315
FBXL17
F-box and leucine-rich repeat protein 17
chr6_-_26197477 0.577 HIST1H3D
histone cluster 1, H3d
chr11_-_45939568 0.575 NM_004813
NM_057174
PEX16

peroxisomal biogenesis factor 16

chr22_-_19511777 0.573 CLDN5
claudin 5
chr15_-_101142375 0.573 NM_001040616
LINS
lines homolog (Drosophila)
chr17_+_46019022 0.572 PNPO
pyridoxamine 5'-phosphate oxidase
chrX_+_52926358 0.569 FAM156B
family with sequence similarity 156, member B
chr14_+_105941061 0.567 NM_001312
CRIP2
cysteine-rich protein 2
chr7_-_65215903 0.564


chr4_-_1685717 0.564 NM_001013622
NM_001174070
FAM53A

family with sequence similarity 53, member A

chr15_-_20711386 0.564 HERC2P3
hect domain and RLD 2 pseudogene 3
chr6_-_32095993 0.563 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chr2_-_240323332 0.563 HDAC4
histone deacetylase 4
chr10_+_96522457 0.560 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr4_-_1722776 0.559 TMEM129
transmembrane protein 129
chr17_-_8055684 0.554 NM_002616
PER1
period homolog 1 (Drosophila)
chr7_+_148982371 0.552 LOC155060
AI894139 pseudogene
chr17_-_43025027 0.549 NM_001080443
KIF18B
kinesin family member 18B
chr19_-_10491172 0.549 TYK2
tyrosine kinase 2
chr1_+_145438437 0.547 NM_006472
TXNIP
thioredoxin interacting protein
chr11_-_568419 0.544 MIR210HG
MIR210 host gene (non-protein coding)
chr12_-_56727446 0.543 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_36915969 0.543 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr11_-_47198379 0.541 ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr20_+_13976263 0.534 MACROD2
MACRO domain containing 2
chr3_-_120461350 0.531


chr1_+_192778168 0.530 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr15_-_23378167 0.528 HERC2P2
hect domain and RLD 2 pseudogene 2
chr16_-_1661969 0.527 NM_014714
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr1_+_227127993 0.524 ADCK3
aarF domain containing kinase 3
chr19_-_15529738 0.523 AKAP8L
A kinase (PRKA) anchor protein 8-like
chr17_-_8198605 0.520 SLC25A35
solute carrier family 25, member 35
chr6_-_27835308 0.518 NM_005322
HIST1H1B
histone cluster 1, H1b
chr22_+_42486904 0.515 LOC100132273
uncharacterized LOC100132273
chr22_-_37172113 0.515 NM_001177701
NM_006860
IFT27

intraflagellar transport 27 homolog (Chlamydomonas)

chr19_+_4969123 0.512 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr3_-_186288331 0.511 NM_001134415
TBCCD1
TBCC domain containing 1
chr9_+_131798899 0.509 FAM73B
family with sequence similarity 73, member B
chr1_+_12079298 0.504 NM_021933
MIIP
migration and invasion inhibitory protein
chr6_-_41863086 0.502 NM_018561
USP49
ubiquitin specific peptidase 49
chr17_+_46048477 0.502 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr9_+_131843378 0.499 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr12_-_15091441 0.498 NM_152321
ERP27
endoplasmic reticulum protein 27
chr1_-_28241233 0.494 NM_002946
RPA2
replication protein A2, 32kDa
chr1_-_149859465 0.493 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr11_-_47198420 0.491 ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr17_-_58212896 0.490


chrX_-_52987610 0.488 NM_001242491
FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chr3_+_50229022 0.488 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr2_+_73144603 0.487 NM_004097
EMX1
empty spiracles homeobox 1
chr19_-_14629227 0.485 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_33172418 0.480 NM_014234
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr17_-_7307413 0.480 NM_152766
C17orf61-PLSCR3
C17orf61
C17orf61-PLSCR3 readthrough
chromosome 17 open reading frame 61
chr17_+_48172508 0.478 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr19_+_50031232 0.476 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr17_-_7197866 0.476 NM_015982
YBX2
Y box binding protein 2
chr1_+_12079522 0.473 MIIP
migration and invasion inhibitory protein
chr3_+_111393522 0.473 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr16_+_57769667 0.472 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr1_+_16062808 0.466 NM_207348
SLC25A34
solute carrier family 25, member 34
chr17_-_7197811 0.465 YBX2
Y box binding protein 2
chr10_-_102790877 0.463 NM_001195263
NM_024895
PDZD7

PDZ domain containing 7

chr19_+_49622480 0.462 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_+_103892 0.461 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_-_178973065 0.458 NM_001077197
PDE11A
phosphodiesterase 11A
chr17_-_3539384 0.456 NM_013276
SHPK
sedoheptulokinase
chr7_-_72298752 0.456 NM_001145440
NM_001145441
TYW1B

tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)

chr4_+_4861371 0.456 NM_002448
MSX1
msh homeobox 1
chr5_-_64858931 0.452 NM_022145
CENPK
centromere protein K
chr6_-_25726754 0.452 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr1_+_64239566 0.452 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr17_+_46048467 0.451 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr11_+_66406087 0.451 NM_001198843
NM_001198844
NM_002896
RBM4


RNA binding motif protein 4


chr16_-_4852571 0.450 NM_024589
ROGDI
rogdi homolog (Drosophila)
chr1_-_26633110 0.450 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr16_+_69984809 0.448 NM_182619
CLEC18C
CLEC18A
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
chr2_+_177053306 0.446 NM_024501
HOXD1
homeobox D1
chr10_-_131909061 0.446 LOC387723
uncharacterized LOC387723
chr8_-_103666018 0.446 NM_001032282
KLF10
Kruppel-like factor 10
chr9_-_35815040 0.443 NM_032593
HINT2
histidine triad nucleotide binding protein 2
chr17_-_79980685 0.441 NM_144998
STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr19_-_10491212 0.439 NM_003331
TYK2
tyrosine kinase 2
chr19_+_55851220 0.438 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr4_-_174255454 0.438 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr19_-_4535202 0.437 NM_001013706
PLIN5
perilipin 5
chr3_-_141868208 0.437 NM_001178138
NM_001178139
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr7_+_129710572 0.436 KLHDC10
kelch domain containing 10
chr5_+_64859098 0.435 NM_015342
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr17_+_46018888 0.433 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr17_-_70116928 0.433 FLJ37644
uncharacterized LOC400618
chr1_+_150459913 0.427 NM_025150
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr19_+_17581276 0.424 NM_198580
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr4_-_1722978 0.423 NM_001127266
NM_138385
TMEM129

transmembrane protein 129

chr19_-_14640048 0.423 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_+_99070428 0.423 ZNF789
zinc finger protein 789
chr6_-_32920812 0.421 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr8_+_118532970 0.421 MED30
mediator complex subunit 30
chr12_-_56211484 0.421 SARNP
SAP domain containing ribonucleoprotein
chr16_+_103859 0.421 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr12_+_50017340 0.420 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr22_+_19701968 0.420 NM_002688
SEPT5
septin 5
chr15_-_83876165 0.420 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr16_-_2723374 0.416 ERVK13-1
endogenous retrovirus group K13, member 1
chr12_+_58087737 0.415 NM_001017956
NM_001017957
NM_001017958
NM_006812
OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr17_+_61627841 0.415 DCAF7
DDB1 and CUL4 associated factor 7
chr10_-_101380217 0.414 NM_031212
SLC25A28
solute carrier family 25, member 28
chr1_+_149824180 0.413 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr20_-_32274154 0.413 NM_005225
E2F1
E2F transcription factor 1
chr19_-_14629160 0.412 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr16_-_30773303 0.412 NM_001014979
NM_001195620
C16orf93

chromosome 16 open reading frame 93

chr19_-_38720312 0.411 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr18_+_44526786 0.408 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr16_-_1876792 0.405 HAGH
hydroxyacylglutathione hydrolase
chr16_-_68482373 0.402 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr3_+_121554029 0.402 NM_018456
EAF2
ELL associated factor 2
chr21_-_47878592 0.401


chr16_+_838610 0.401 NM_022092
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr19_-_36545646 0.398 NM_152658
THAP8
THAP domain containing 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
42.44 2.35e-03 GO:0006334 nucleosome assembly
40.25 2.75e-03 GO:0031497 chromatin assembly
38.28 3.20e-03 GO:0034728 nucleosome organization
36.84 3.59e-03 GO:0065004 protein-DNA complex assembly
34.87 4.23e-03 GO:0071824 protein-DNA complex subunit organization
30.76 6.16e-03 GO:0006323 DNA packaging
28.94 7.39e-03 GO:0006333 chromatin assembly or disassembly
26.41 9.71e-03 GO:0071103 DNA conformation change
3.52 9.87e-03 GO:0016043 cellular component organization
12.19 1.11e-02 GO:0006325 chromatin organization
5.44 1.21e-02 GO:0006996 organelle organization
3.41 1.26e-02 GO:0071840 cellular component organization or biogenesis
3.95 1.90e-02 GO:0071842 cellular component organization at cellular level
3.81 2.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
9.39 3.05e-02 GO:0051276 chromosome organization

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
65.03 2.53e-04 GO:0000786 nucleosome
41.10 1.01e-03 GO:0032993 protein-DNA complex
17.02 1.39e-02 GO:0000785 chromatin

Nothing significant found in function category.